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Mass Spectrometry in Sports Drug Testing: Characterization of Prohibited Substances and Doping Control Analytical Assays (2010) by Mario Thevis [Dr Soc]

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  Mass Spectrometry in Sports Drug Testing:
Characterization of Prohibited Substances and Doping Control Analytical Assays by Mario Thevis
  English | 2010
| ISBN: 0470413271 | 360 pages | PDF | 6.06 MB
  
  Enables you to detect, identify, and characterize hundreds
of drugs that may be used by athletes
  
  Mass spectrometry has become essential to sports drug testing. This
book examines both the principles of sports drug testing and the use of mass spectrometry techniques and mass spectral
data to detect, identify, and characterize hundreds of known and unknown drugs that athletes may use to enhance their
performance. The author provides a detailed overview of the mass spectrometry of numerous classes of therapeutics and
agents, various analyzers to detect low- and high-molecular weight drugs, as well as techniques to discriminate between
endogenously produced and synthetically derived compounds.
  
  Mass Spectrometry in Sports Drug Testing
begins with a full chapter dedicated to the history of sports drug testing. Next, the book provides the principles and
techniques needed to maximize the specificity and sensitivity of mass spectrometric assays, including:
  -
Detailed, step-by-step assays with sample preparation
  - Discussion of both chromatographic separation and mass
spectrometric analysis
  - Characterization of analytes in order to unequivocally identify banned substances
 
- Mass spectrometric behavior of low- and high-molecular weight analytes
  
  Throughout the book, descriptive
examples illustrate the principles, advantages, and limitations of different assays.
  
  Mass Spectrometry in
Sports Drug Testing not only sets forth the role mass spectrometry plays in detecting drug use among athletes, it also
adds new insights into the health and ethical issues of doping in sports.
  
  
  
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